Remarkable kinetic resolution of chiral β-keto esters by baker's yeast reduction

authored by
Marcus Eh, Markus Kalesse
Abstract

The reduction of chiral β-keto esters with baker's yeast is described. Reduction of 10 yields highly functionalized diol 11 with excellent stereoselectivity and generates a useful intermediate for natural product syntheses.

Organisation(s)
Institute of Organic Chemistry
Type
Article
Journal
SYNLETT
Volume
1995
Pages
837-838
No. of pages
2
ISSN
0936-5214
Publication date
08.1995
Publication status
Published
Peer reviewed
Yes
ASJC Scopus subject areas
Organic Chemistry
Electronic version(s)
https://doi.org/10.1055/s-1995-5083 (Access: Unknown)