Investigation of adaptive muscle synergy modulated motor responses to grasping perturbations

authored by: Eike Jakubowitz, Leonard Schmidt, Alina Obermeier, Svenja Spindeldreier, Henning Windhagen, Christof Hurschler
Abstract: This study investigated how muscle synergies adapt in response to unexpected changes in object weight during lifting tasks. The aim was to discover which motor control strategies individuals use to maintain their grasping performance. Muscle synergies were extracted from the muscle activity of fifteen healthy participants who lifted objects of identical appearance but varying weights in a randomized order, which introduced artificial perturbations. Reaching and manipulation phases of object lifting were analyzed using constrained non-negative matrix factorization and k-means clustering. Participants exhibited a perturbation-independent and thus consistent recruitment of spatial synergy components, while significant adaptations in muscle synergy activation occurred in response to unexpected perturbations. Perturbations caused by unexpectedly heavy objects led to delayed and gradual increases in muscle synergy activation until the force required to lift the object was reached. In contrast, perturbations caused by lighter objects led to reductions in excess muscle synergy activation occurring later. Sensorimotor control maintains the modularity of muscle synergies. Even when external mechanical perturbations occur, the grasping performance is preserved, and control is adapted solely through muscle synergy activation. These results suggest that using pure spatial synergy components as control signals for myoelectric arm prostheses may prevent them from malfunctioning due to external perturbations.
Organisation(s): Institute of Mechatronic Systems
External Organisation(s): Hannover Medical School (MHH)
Type: Article
Journal: Scientific reports
Volume: 14
No. of pages: 9
ISSN: 2045-2322
Publication date: 12.2024
Publication status: Published
Peer reviewed: Yes
ASJC Scopus subject areas: General
Electronic version(s): https://doi.org/10.1038/s41598-024-68386-8 (Access: Open)

BibTeX

@article{d1d54e963f0f43cbb35ccb560a239ff5,
title = "Investigation of adaptive muscle synergy modulated motor responses to grasping perturbations",
abstract = "This study investigated how muscle synergies adapt in response to unexpected changes in object weight during lifting tasks. The aim was to discover which motor control strategies individuals use to maintain their grasping performance. Muscle synergies were extracted from the muscle activity of fifteen healthy participants who lifted objects of identical appearance but varying weights in a randomized order, which introduced artificial perturbations. Reaching and manipulation phases of object lifting were analyzed using constrained non-negative matrix factorization and k-means clustering. Participants exhibited a perturbation-independent and thus consistent recruitment of spatial synergy components, while significant adaptations in muscle synergy activation occurred in response to unexpected perturbations. Perturbations caused by unexpectedly heavy objects led to delayed and gradual increases in muscle synergy activation until the force required to lift the object was reached. In contrast, perturbations caused by lighter objects led to reductions in excess muscle synergy activation occurring later. Sensorimotor control maintains the modularity of muscle synergies. Even when external mechanical perturbations occur, the grasping performance is preserved, and control is adapted solely through muscle synergy activation. These results suggest that using pure spatial synergy components as control signals for myoelectric arm prostheses may prevent them from malfunctioning due to external perturbations.",
keywords = "External perturbation, Grasping performance, Motor control strategies, Muscle synergies, Myoelectric arm prostheses, Object lifting",
author = "Eike Jakubowitz and Leonard Schmidt and Alina Obermeier and Svenja Spindeldreier and Henning Windhagen and Christof Hurschler",
note = "Publisher Copyright: {\textcopyright} The Author(s) 2024.",
year = "2024",
month = dec,
doi = "10.1038/s41598-024-68386-8",
language = "English",
volume = "14",
journal = "Scientific reports",
issn = "2045-2322",
publisher = "Nature Publishing Group",
number = "1",
}