The "resin-capture-release" hybrid technique

A merger between solid- and solution-phase synthesis

verfasst von

Andreas Kirschning, Holger Monenschein, Rüdiger Wittenberg

Abstract

A polymer-assisted organic synthesis that combines the concept of solid-phase synthesis with the idea of polymer-supported scavenging reagents has recently appeared on the chemistry scene. This technique has frequently been termed the "resin-capture-release" methodology and is initiated by the immobilization of a small molecule on a polymeric support. This intermediate is subjected to a second transformation by adding a new reaction partner in solution. This reactant plays two roles: a) the chemical alteration of the polymer-bound intermediate and b) the simultaneous release of this reaction product from the resin back into solution. This new concept is presented and future prospects are discussed.

Organisationseinheit(en)

Institut für Organische Chemie

Externe Organisation(en)

Technische Universität Clausthal

Typ

Artikel

Journal

Chemistry - A European Journal

Band

6

Seiten

4445-4450

Anzahl der Seiten

6

ISSN

0947-6539

Publikationsdatum

27.11.2000

Publikationsstatus

Veröffentlicht

Peer-reviewed

Ja

ASJC Scopus Sachgebiete

Katalyse, Organische Chemie

Elektronische Version(en)

https://doi.org/10.1002/1521-3765(20001215)6:24<4445::AID-CHEM4445>3.0.CO;2-W (Zugang: Unbekannt)