Synthesis of isotopically labelled 3-amino-2-phenylpropionic acid and its role as a precursor in the biosynthesis of tenellin and tropic acid
- authored by
- Russell J. Cox, David O'Hagan
- Abstract
A synthesis of [3-13C]- and [3-14C]-3-amino-2- phenylpropionic acids 7a and 7b is described. The incorporation of this amino acid into tenellin 1 from Beauveria bassiana (Bals.) Vuill. and into tropic acid 10 moiety of the tropane alkaloids hyscoyamine 8 and scopolamine 9 from Datura innoxia was studied but proved unsuccessful in each case.
- External Organisation(s)
-
University of Durham
- Type
- Article
- Journal
- Journal of the Chemical Society, Perkin Transactions 1
- Pages
- 2537-2540
- No. of pages
- 4
- ISSN
- 1472-7781
- Publication date
- 01.12.1991
- Publication status
- Published
- Peer reviewed
- Yes
- ASJC Scopus subject areas
- General Chemistry
- Electronic version(s)
-
https://doi.org/10.1039/p19910002537 (Access:
Unknown)