Surface-Enhanced Raman Spectroscopy on Selectively Adsorbed Plasmonic Nanostructures Using Polar Surface Arrays

authored by: Zunhao Wang, Zhe Liu, Wibke Dempwolf, Julia Molle, Yuya Kanehira, Sergio Kogikoski, Markus Etzkorn, Ilko Bald, Rainer Stosch, Stefan Wundrack
Abstract: This paper introduces an approach that enables highly adjustable surface adsorption of single plasmonic nanostructures using polar surface arrays. The plasmonic nanostructures are made from DNA origami and functionalized with gold nanoparticles for surface-enhanced spectroscopic techniques. To ensure that the contribution of individual nanostructures to the measured signal can be detected without any interference from the surrounding structures, we aimed to control the distance and set a minimum gap between the nanostructures on the substrate surface. We describe the fabrication process of the polar surface array based on electron beam lithography, followed by functionalization. Our results indicate that the concentration of DNA origami structures and the duration of the incubation primarily affect the number of adsorbed nanostructures. Density functional theory simulation explains the selective adsorption of plasmonic nanostructures due to the substrate surface properties. The spatial arrangement of nanostructures allows for the reliable identification of the Raman signal’s location, while a falsified identification resulting from agglomeration is prevented.
External Organisation(s): National Metrology Institute of Germany (PTB)
Technische Universität Braunschweig
University of Potsdam
Type: Article
Journal: ACS Applied Nano Materials
Volume: 6
Pages: 14645–14655
No. of pages: 11
Publication date: 25.08.2023
Publication status: Published
Peer reviewed: Yes
ASJC Scopus subject areas: Materials Science(all)
Electronic version(s): https://doi.org/10.1021/acsanm.3c01776 (Access: Closed)

BibTeX

@article{4be73fea19154b8696c054ea0b1ca8cf,
title = "Surface-Enhanced Raman Spectroscopy on Selectively Adsorbed Plasmonic Nanostructures Using Polar Surface Arrays",
abstract = "This paper introduces an approach that enables highly adjustable surface adsorption of single plasmonic nanostructures using polar surface arrays. The plasmonic nanostructures are made from DNA origami and functionalized with gold nanoparticles for surface-enhanced spectroscopic techniques. To ensure that the contribution of individual nanostructures to the measured signal can be detected without any interference from the surrounding structures, we aimed to control the distance and set a minimum gap between the nanostructures on the substrate surface. We describe the fabrication process of the polar surface array based on electron beam lithography, followed by functionalization. Our results indicate that the concentration of DNA origami structures and the duration of the incubation primarily affect the number of adsorbed nanostructures. Density functional theory simulation explains the selective adsorption of plasmonic nanostructures due to the substrate surface properties. The spatial arrangement of nanostructures allows for the reliable identification of the Raman signal{\textquoteright}s location, while a falsified identification resulting from agglomeration is prevented.",
keywords = "controlled physisorption, DNA origami, Langmuir isotherm, self-assembled monolayers, single molecule detection, surface functionalization, surface-enhanced Raman scattering",
author = "Zunhao Wang and Zhe Liu and Wibke Dempwolf and Julia Molle and Yuya Kanehira and Sergio Kogikoski and Markus Etzkorn and Ilko Bald and Rainer Stosch and Stefan Wundrack",
note = "Funding information: This work was financially supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) Research Training Group GrK1952/2, Metrology for Complex Nanosystems (NanoMet). Furthermore, this work was supported by the Braunschweig International Graduate School of Metrology (B-IGSM) and the Laboratory for Emerging Nanometrology (LENA) of TU Braunschweig. We thank the high-performance computer cluster (HPC) of PTB on which the DFT simulations were carried out. Z.L. acknowledges funding by the Deutsche Forschungsgemeinschaft (DFG) under Germany{\textquoteright}s Excellence Strategy–EXC 2123 QuantumFrontiers, Project ID: 390837967, as well as from the Ministry of Science and Culture of Lower Saxony under the project QuanTec., Project ID: 76251 (ZN 3820). We acknowledge DFG funding under grant INST 188/452-1 FUGG. XPS measurements have been performed on an instrument supported by the DFG (INST 188/444-1 FUGB). Y.K. and S.K. acknowledge funding by the European Research Council (ERC; consolidator grant no. 772752)",
year = "2023",
month = aug,
day = "25",
doi = "10.1021/acsanm.3c01776",
language = "English",
volume = "6",
pages = "14645–14655",
journal = "ACS Applied Nano Materials",
issn = "2574-0970",
publisher = "American Chemical Society",
number = "16",
}