Clinical equipoise

Why still the gold standard for randomized clinical trials?

verfasst von

Charlemagne Asonganyi Folefac, Hugh Desmond

Abstract

The principle of clinical equipoise has been variously characterized by ethicists and clinicians as fundamentally flawed, a myth, and even a moral balm. Yet, the principle continues to be treated as the de facto gold standard for conducting randomized control trials in an ethical manner. Why do we hold on to clinical equipoise, despite its shortcomings being widely known and well-advertised? This paper reviews the most important arguments criticizing clinical equipoise as well as what the most prominent proposed alternatives are. In the process, it evaluates the justification for continuing to use clinical equipoise as the gold standard for randomized control trials.

Externe Organisation(en)

KU Leuven
Aarhus University
Universiteit Antwerpen (UAntwerpen)
Centre national de la recherche scientifique (CNRS)

Typ

Artikel

Journal

Clinical Ethics

Band

19

Seiten

102-112

Anzahl der Seiten

11

ISSN

1477-7509

Publikationsdatum

03.2024

Publikationsstatus

Veröffentlicht

Peer-reviewed

Ja

ASJC Scopus Sachgebiete

Medizin (sonstige), Probleme, Ethik und rechtliche Aspekte, Philosophie

Elektronische Version(en)

https://doi.org/10.1177/14777509221121107 (Zugang: Geschlossen)