Biosensors for enantioselective analysis

verfasst von

Thomas Kullick, Roland Ulber, Hartmut H. Meyer, Thomas Scheper, Karl Schügerl

Abstract

The development of enantioselective enzyme field effect transistors (EnFETs) for the detection of β-hydroxy acid esters and aromatic amino esters and their application in flow-injection analysis is described. The EnFETs were produced by immobilising the enzyme on the pH-sensitive gate surface of a pH-FET. The characteristics of the sensor signals and their dependence on certain process parameters, such as pH, buffer capacity and flow conditions in the medium being measured, were examined. Due to the short response time, the EnFETs are ideal for application in flow-injection analysis. The use of enantioselective EnFETs in on-line process monitoring is described.

Externe Organisation(en)

Westfälische Wilhelms-Universität Münster (WWU)

Typ

Artikel

Journal

Analytica chimica acta

Band

293

Seiten

271-276

Anzahl der Seiten

6

ISSN

0003-2670

Publikationsdatum

29.07.1994

Publikationsstatus

Veröffentlicht

Peer-reviewed

Ja

ASJC Scopus Sachgebiete

Analytische Chemie, Biochemie, Umweltchemie, Spektroskopie

Elektronische Version(en)

https://doi.org/10.1016/0003-2670(94)85032-1 (Zugang: Unbekannt)